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Arthur M Brown Selected Research

vanoxerine (I 893)

11/2015Quantitative Profiling of the Effects of Vanoxerine on Human Cardiac Ion Channels and its Application to Cardiac Risk.
6/2015COR-ART: A multicenter, randomized, double-blind, placebo-controlled dose-ranging study to evaluate single oral doses of vanoxerine for conversion of recent-onset atrial fibrillation or flutter to normal sinus rhythm.
11/2011Oral vanoxerine prevents reinduction of atrial tachyarrhythmias: preliminary results.
3/2010Vanoxerine, a new drug for terminating atrial fibrillation and flutter.
3/2010Vanoxerine: cellular mechanism of a new antiarrhythmic.

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Arthur M Brown Research Topics

Disease

7Torsades de Pointes (Torsade de Pointes)
07/2013 - 07/2004
5Atrial Fibrillation
11/2015 - 03/2010
5Long QT Syndrome
01/2009 - 01/2002
4Cardiac Arrhythmias (Arrythmia)
03/2014 - 02/2002
3Atrial Flutter (Flutter, Atrial)
06/2015 - 03/2010
3Cardiomyopathies (Cardiomyopathy)
11/2003 - 02/2003
3Iron Overload
11/2003 - 02/2003
2Cardiovascular Diseases (Cardiovascular Disease)
03/2014 - 03/2010
2Cardiotoxicity
10/2013 - 07/2005
2Pericarditis
11/2011 - 03/2010
2Atrioventricular Block
08/2003 - 02/2003
1Parkinsonian Disorders (Parkinsonism)
11/2015
1Cocaine-Related Disorders (Cocaine Addiction)
11/2015
1Ventricular Tachycardia
06/2015
1Pain (Aches)
03/2014
1Hypertension (High Blood Pressure)
03/2014
1Neoplasms (Cancer)
10/2013
1Tachycardia (Tachyarrhythmias)
11/2011
1Opioid-Related Disorders (Opiate Addiction)
10/2010
1Cardiac Sudden Death (Sudden Cardiac Arrest)
10/2010
1Chronic Pain
10/2010
1Sudden Death
10/2010
1Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
01/2005
1Leishmaniasis
01/2005
1Trypanosomiasis
01/2005
1Acute Promyelocytic Leukemia
07/2004
1Cardiomegaly (Heart Hypertrophy)
11/2003
1Atrophy
04/2003
1Ventricular Premature Complexes (Premature Ventricular Contraction)
02/2003
1Bradycardia
02/2003
1Heart Failure
02/2003
1Infections
05/2002
1Prostatic Neoplasms (Prostate Cancer)
05/2002

Drug/Important Bio-Agent (IBA)

6Pharmaceutical PreparationsIBA
10/2013 - 07/2005
5vanoxerine (I 893)IBA
11/2015 - 03/2010
5Potassium Channels (Potassium Channel)IBA
01/2013 - 05/2002
3Ether (Diethyl Ether)IBA
10/2013 - 02/2002
3Anti-Arrhythmia AgentsIBA
07/2013 - 07/2005
3IronIBA
11/2003 - 02/2003
2CalciumIBA
03/2014 - 07/2004
2Arsenic Trioxide (Trisenox)FDA Link
01/2005 - 07/2004
2Dextrans (Dextran)FDA Link
11/2003 - 02/2003
2Deferoxamine (Desferal)FDA LinkGeneric
11/2003 - 02/2003
2Chelating AgentsIBA
11/2003 - 02/2003
1Tyrosine Kinase InhibitorsIBA
10/2013
1Diazepam (Valium)FDA LinkGeneric
10/2010
1Opioid Analgesics (Opioids)IBA
10/2010
1BenzodiazepinesIBA
10/2010
1Methadone (Dolophine)FDA LinkGeneric
10/2010
1Amiodarone (Amiodarona)FDA LinkGeneric
03/2010
1Pentamidine (NebuPent)FDA LinkGeneric
01/2005
1Aligeron (AS 2)IBA
07/2004
1SodiumIBA
08/2003
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2003
1CaspasesIBA
04/2003
1Proteins (Proteins, Gene)FDA Link
05/2002
1StaurosporineIBA
05/2002
1Ion Channels (Ion Channel)IBA
01/2002

Therapy/Procedure

2Subcutaneous Injections
11/2003 - 02/2003
1Electric Countershock (Cardioversion)
06/2015